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BIO3R represents a consortium composed of 20 partners from 8 European Countries (Belgium, United Kingdom, France, Germany, Italy, the Netherlands, Poland, Sweden). It constitutes a unique team of multidisciplinary competences linking Strategic Research Centres and ¡°think tanks¡± (IAI, IABG, FOI, FRS, TNO, UoR), Laboratories and Research Centres (CEB, CNES, WIHE.PL, UCL), Industry (Bertin, Sagem, Multitel), hospitals and medical research institutes (RKI, UKB, UHP, UP7DD, HBichat), as well as providers of Health Research Policy (Nomisma) and Water Safety (Eau de Paris).

1 ¨C FONDATION POUR LA RECHERCHE STRATÉGIQUE - FRS (FR)

Core business and skills

Based in Paris, FRS is one of the most prominent independent French research institutes in the field of Security and Defence. As a public-interest foundation, it carries out research work and studies in the field of security and defence with the aim of bringing an independent expertise to interested decision-makers, either public or private.

The FRS has three main fields of research: Terrorism and Defence issues; Technology, Space and Security and Analysis of conflict context and situations. It has long had a commitment to the study of terrorism and more precisely non conventional terrorism (CBRN).

Role in the project

FRS, which will coordinate BIO3R, will be responsible for the management and for the synthesis and dissemination of the results (with University of Reading). In addition, it will contribute to the threat analysis, with the description of plausible scenarios for a bioterrorism event, and to the characterisation of the resulting operational requirements.

www.frstrategie.org

2 ¨C BERTIN Technologies - BER (FR)

Core business and skills

Bertin Technologies is recognised as an innovation force toward new services and products involving high technological content in relation to engineering activities and life sciences. With a highly skilled workforce of 230, Bertin Technologies can act as an "expert" or as an "equipment developer" to major system manufacturers and administrative customers. Defence, Homeland Security and Health are major fields of activity representing some 70 % of the turnover and order book.

Bertin Technologies has acquired a great deal of experience over the past few years in the development of technologies to perform main functions of the overall biological identification chain, (such as alert detection, bio-sampling, sample preparation, bio-analysis), in the provision of expert assessments for different operational needs like bio-contamination monitoring of clean rooms in the food and pharmaceutical industries, or bio-diagnosis in food production (BSE, Salmonella), and in the bio-surveillance of the environment for public health (Legionella) or defence (large military zones). Several advanced technologies have been developed in this context, like bio-aerosol cyclonic collectors, immuno-analysis automated equipment and associated reagents, sensitive DNA microchip identification process.

Finally, Bertin Technologies has recently acquired an extensive knowledge of state-of-the-art techniques for the modelling of epidemics through work performed for the French MoD (project MODEPI).

Role in the project

As an expert in biotechnologies and in technologies related to the overall chain of biological identification functions like warning, bio-sampling, sample preparation, bio-analysis, Bertin Technologies will make a major contribution to the investigation of sensor technologies best suited to the bio-threat scenarios that will be selected in this project. Based on their recent experience, and supplemented other expert input both within the project team and beyond (selected interviews of the most advanced groups in Europe), Bertin Technologies will also provide an analysis of the potential of epidemic modelling in the operational management of bio-crises at the different stages of anticipation, prevention and reaction.

www.bertin.fr

3 ¨C CENTRE D¡¯ÉTUDES DU BOUCHET - CEB (FR)

Core business and skills

Part of DGA (D¨¦l¨¦gation G¨¦n¨¦rale pour l¡¯Armement), the CEB (Centre d¡¯Études du Bouchet) is the expert centre of the French MoD for the CBRN (Chemical, Biological, Radiological, and Nuclear) defence. Its main missions are: characterisation of the NRBC threat, which involves the knowledge of the nature and the effects of nuclear, radiological, chemical and pathogenic biological agents, evaluation of the effects of the dispersion of RBC agents using mathematical models, public service missions such as participation in the actions against bio-terrorism and chemical terrorism, as well as judicial expertise.

To fulfil these missions, the CEB has several laboratories and installations for test equipments especially well adapted to work with toxic agents (chemical and biological)

Role in the project

Thanks to its solid background in the NRBC field, the CEB will actively contribute to the evaluation of scenario modelling capabilities, and the Detection, Identification Protection, Decontamination & Restoration analyses.

4 ¨C CENTRE NATIONAL D¡¯ÉTUDES SPATIALES - CNES (FR)

Core business and skills

Founded in 1961, the Centre National d¡¯Études Spatiales (CNES) is the government agency responsible for shaping and implementing France¡¯s space policy in Europe. Its task is to invent the space systems of the future, bring space technologies to maturity and guarantee France¡¯s independent access to space.

CNES is a pivotal player in Europe¡¯s space programme, and a major source of initiatives and proposals that aim to maintain France and Europe¡¯s competitive edge. It conceives and executes space programmes with its partners in the scientific community and industry, and is closely involved in many international cooperation programmes, the key to any far-reaching space policy.

The agency¡¯s more-than 2,400-strong workforce constitutes an exceptional pool of talent, with some 1,800 engineers and executives, 35 % of whom are women.

Through its ability to innovate and its forward-looking vision, CNES is helping to foster new technologies that will benefit society as a whole, focusing on:

¡¤                     access to space

¡¤                     civil applications of space

¡¤                     sustainable development

¡¤                     science and technology research

¡¤                     security and defence

In the specific field of application related to BIO3R, CNES has developed applications that bring together all satellites capabilities to collect data from remote isolated sites, to monitor and forecast the evolution of environment related diseases, in order to provide new challenging services in the domains of health, risk and crisis management. Successful demonstrations have been made in several countries.

CNES is member of S2E consortium (Surveillance Spatiale des Epid¨¦mies, Epidemy monitoring using space techniques) that promotes the development of early warning networks using space techniques in the domain of tele-epidemiology with a climate/environment/health approach. S2E consortium gathers CNES and its subsidiaries (MEDES, MEDIAS, CLS), Institut Pasteur, INRA and Lyon Veterinarian School. S2E consortium is implicated in several early warning systems: Dengue in Argentina, West Nile in Africa, Avian influenza in China...

Role in the project

Thanks to its experience in epidemiology and risk management, CNES will contribute to epidemiological modelling and to operational actors¡¯ coordination tools.

www.cnes.fr

5 ¨C EAU DE PARIS - EdP (FR)

Core business and skills

Eau de Paris is a mixed public-private company of the City of Paris in charge of water management. Its purpose is to produce and transport the 615 000 cubic metres of drinking water daily consumed in Paris.

Its ambition is to anticipate and to work for sustainable guarantees for safe, high quality drinking water for Paris, thanks to a proactive prevention and resource protection policy.

It is also involved in international cooperation, through solidarity missions (e.g. Mali) and technical assistance missions (e.g. Vietnam and Laos).

Role in the project

Eau de Paris provides leading expertise in various fields related to water, and thus will contribute to the threat analysis and scenarios on the aspects linked to water contamination, as well as participating in the operational users¡¯ workshop.

www.eaudeparis.fr

6 ¨C SWEDISH DEFENCE RESEARCH AGENCY - FOI (SE)

Core business and skills

FOI is an assignment-based authority under the Ministry of Defence. The core activities are research, method and technology development, as well as studies for the use of defence and security.  

The organisation employs around 1 350 people of whom around 950 are researchers. This makes FOI the largest research institute in Sweden.  

FOI provides leading expertise in a large number of fields such as security-policy studies and analyses in defence and security, assessment of different types of threats, systems for control and management of crises, protection against and management of hazardous substances, IT-security and the potential of new sensors.

Role in the project

Thanks to its expertise in the fields of research, defence and security, FOI will have a role in the threat assessment and in the identification of plausible scenarios for a bio-attack, as well as in the part dedicated to the crisis management and restoration.

www.foi.se

7 ¨C GROUPE HOSPITALIER PITIÉ-SALPÊTRIÈRE - GHPS (FR)

Core business and skills

Through its department of bacteriology and hygiene, directed by Professor JARLIER, the hospital is involved in the evaluation of antibiotic resistance (National References Centre). 

Role in the project

GHPS will be leader in the education and training part, with the development of tools for the first line responders in hospitals and laboratories.

8 ¨C INDUSTRIEANLAGEN-BETRIEBSGESELLSCHAFT mbH - IABG (DE)

Core business and skills

IABG was founded in 1961 by the German Government as a central analysis and testing organization for Aerospace industries and the Ministry of Defence. Privatized in 1993, IABG is today a leading European technical-scientific service enterprise. It has more than 1.000 employees in 12 European locations with the Headquarters in Ottobrunn/Munich.

IABG provides analytic, technical and operational solutions in the areas of security and defence, Info-Com, aeronautics, space, automotive, transport, environment. IABG runs test centres for the European Space Agency, transformation centres for the Bundeswehr, a life-science-solution centre et al. Security and defence make up 40 % of the revenue.

Role in the project

IABG¡¯s expertise will be useful in the field of threat analysis and for the definition of plausible scenarios.

www.iabg.de

9 ¨C ISTITUTO AFFARI INTERNAZIONALI - IAI (IT)

Core business and skills

The Istituto Affari Internazionali (IAI), a non-profit organisation, is funded by individual and corporate members, public and private organisations, major international foundations, and by a standing grant from the Italian Ministry of Foreign Affairs.

The Institute's main objective is to promote an understanding of the international problems.

Main experiences in the field of security research:

¡¤                     IAI has developed significant expertise in organising and bringing together the security user community, meaning bringing the expertise of the main security users into technological projects (such as police forces, defence administration, customs¡­). IAI also ensures the strategic coherence of such projects with the main security policies in Europe, such as ¡°security of the citizen¡± and the European Strategy for Security.

¡¤                     IAI has a long tradition in developing security scenarios.

Role in the project

IAI will provide:

¡¤                     an expertise in security policy and scenarios drafting,

¡¤                     a network of users, expertise for interviews and workshops with security officers,

¡¤                     a network of partners¡¯ institutes that can provide the same level of expertise and contacts for each European country,

¡¤                     an overall capacity in strategic analysis and linkage to the main policies for security (dissemination).

It will also contribute to the analyses on the crisis management.

www.iai.it

10 ¨C MULTITEL - MULT (BE)

Core business and skills

Multitel is a research centre working on Telecommunication and Signal Processing. There are five fields of activity in the centre: speech and signal processing, image processing, networking, photonics and optical communications.

Two of these 4 departments will be involved in the ¡°BIO3R¡± project.

¡¤                     The signal processing department with its valuable expertise on collaborative networks through its involvement in the EUREKA ITEA LASCOT project (LArge Scale COllaborative decision support Technology). The objective of the LASCOT project was the development of tools to enable collaborative decision-making between various stakeholders. One of the scenarios concerned bio-terrorism.

¡¤                     The Applied Photonics department focusing on the design, prototyping and applications of optical fibre based lasers and components. Typically the department is involved in the development of:

.optical fibre sensors and bio-sensors and

.narrow-band, tuneable and high-power fibre lasers, which are used for sensing, lidar, telecom, medicine and material processing.

Role in the project

Multitel is involved in the part dealing with the detection and identification, thanks to its expertise in bio-sensors. The contribution of the Applied Photonics Department will consist in the description and comparison of some methods, based on optical fibre technology (optical fibre biosensors), that can be used for identifying a number of dangerous bio-chemical species. More specifically, this department will evaluate the aspects related to the sensibility, stability and repeatability of such an optical detection.

In addition it will investigate the possibility of using an optical fibre detection technique for the early warning on the presence of bio-chemical molecules in several practical situations and environments (some specific points will be studied, for instance the possibilities of using reduced cost optical fibre bio-sensors in environments such as the airports, where this type of sensor will be critical to detect in real time and at low concentration the presence in the air of specific substances related to a possible bio-terrorist attack).

 Thanks to its expertise in collaborative decision making, the R&D Centre will lead the team dedicated to the coordination of operational actors and networks. 

www.multitel.be

11 ¨C NOMISMA  S.p.A. - NOMISMA (IT)

Core business and skills

Founded in Bologna in 1981, by a group of leading economists, Nomisma is a limited company. Originally established as a research institute to study and analyse the features and dynamics of the real economy at the regional, national and international levels, over the course of its evolution, Nomisma began providing consultancy and technical assistance services as well, first in the Italian home market and then abroad. Currently, Nomisma comprises several research and consultancy units, each specialising in a different field, including Health System and Policies, International Security and Strategic Scenarios.

Nomisma's research approach seeks to understand the complexity of pluralistic systems in different contexts. Therefore, the focus is on both economic and policy spheres as well as the interplay between the two. Also, the dynamics of innovation in research and technology development (RTD) are carefully assessed. Research projects have been developed to examine the topics of process and product innovation, management of innovation, business process innovation, and, recently, on the innovative impact of information technologies.

Role in the project

Nomisma will deal with legal and social aspects. It will also be involved in the part concerning resilience, including medical countermeasures, crisis management and cross evaluation health policies.

www.nomisma.it

12 - ROBERT KOCH-INSTITUT - RKI (DE)

Core business and skills

The Centre for Biological Security (Zentrum f¨¹r Biologische Sicherheit, ZBS) is the central institution for issues of biological Security. The centre¡¯s tasks include, in close cooperation with the other departments of the Robert Koch Institut, the development of concepts for identifying attacks with biological agents using epidemiological analyses and investigative epidemiology in addition to the diagnostics of relevant pathogens (prevention, identification and defence).

The ZBS is divided into a Federal Information Centre for Biological Security (Informationsstelle des Bundes f¨¹r Biologische Sicherheit, IBBS) and four departments (ZBS 1-4). The ZBS collaborates routinely with the relevant institutions for civil defence, with federal states and town councils (including institutions for civil protection). The ZBS functions in accordance with the Federal Ministry for Health at an international level, particularly within the EU:

- Federal Information Centre for Biological Security (IBBS). It has a wide expertise in the fields of: 

¡¤                     Scenario modelling from the perspective of the specificities of bio-terrorist attacks

¡¤                     Evaluation of the origin of disease outbreaks;

¡¤                     Modes of dissemination, sample collection, detection;

¡¤                     Establishment and development of information networks and cooperation;

¡¤                     Coordination of measures for the defence against bio-terrorist pathogens;

¡¤                     Recommendations and guidelines for unusual epidemics;

¡¤                     Assessment of needs for diagnostics, anti-infectious agents, vaccines and other pharmaceuticals;

¡¤                     Collaboration with authorities of other departments;

¡¤                     Processing of scientific data;

¡¤                     Establishment of databases on bio-terrorism;

¡¤                     Providing information to the general public;

¡¤                     Providing information to the scientific sector;

¡¤                     Providing information to the political decision makers;

¡¤                     Media-related work in coordination with the institute's management and press department.

The IBBS collaborates with the EU Network on Bio-terrorism (BICHAT) in accordance with the Federal Ministry of Health and Social Security (BMGS) and with the Public Health directorate of the European Commission. It also has contacts with the corresponding civil and military institutions both within and outside the EU, the WHO, FAO and other UN institutions, and there are cooperation with relevant national and international scientific institutions. The IBBS also takes part in the implementation of national and international specialists¡¯ forums.

- ZBS 1 Highly Pathogenic Viruses

- ZBS 2 Highly Pathogenic Microbial Pathogens ¨C Bacteria and Fungi

- ZBS 3 Microbial Toxins

-ZBS 4 Imaging Techniques & Rapid, Morphology-Based Diagnostics of Infectious Organisms

Role in the project

RKI will have a key role in the part about crisis management and restoration, and contribute to the team dedicated to the medical countermeasures.

www.rki.de

13 ¨C SAGEM DEFENCE SECURITY- SDS (FR)

Core business and skills

Sagem Defence Security (Sagem DS) is the subsidiary of the newly born SAFRAN group (10,4 G€ turnover 2004, 55 000 persons working mainly in aeronautics equipment and engines) and represents the whole branch of the group in the field of defence and security equipment and systems with a turnover of 1,2 G€ and 6 756 persons). Sagem is an internationally-based high-technology group. The second largest French group in the field of telecommunications and the third largest European company in electronics for defence and security, Sagem maintains a presence in more than twenty countries.

Regarding the project, Sagem is Europe's leading manufacturer in inertial systems and third in the world, European leader in optronic systems, world leader in fingerprint-based biometrics (biometric identification and systems, secure terminals, smart cards and certification).

Role in the project

By tracking infection through different means, the propagation of bio-agent will be defined and displayed. The protection of the population or the definition of an 'at risk area' would thus be easier to enforce. Because of its expertise in sensors, Sagem will define the tracking, tracing and identification capabilities of those sensors, their efficiency and reliability in this type of situations, and the analysis of the collected data.

www.sagem.com

14 - NETHERLANDS ORGANISATION FOR APPLIED SCIENTIFIC RESEARCH TNO - TNO (NL)

Core business and skills

TNO is an independent research organisation, making knowledge applicable for companies, government bodies and public organisations. TNO employs some 5,000 employees who develop and apply knowledge. TNO provides contract research and specialist consultancy, tests and certifies products and services, and issues an independent evaluation of quality. TNO is active in five core areas: TNO Quality of Life, TNO Defence, Security and Safety, TNO Science and Industry, TNO Built Environment and Geosciences, and TNO Information and Communication Technology.

Role in the project

TNO will participate in work on Threat analysis (scenarios & modelling) and Detection and  identification. As coordinator of the project IMPACT (PASR-2004), TNO will provide relevant input from IMPACT into BIO3R.

www.tno.nl

15 ¨C UNIVERSITÉ CATHOLIQUE DE LOUVAIN - UCL (BE)

Core business and skills

The Applied Molecular Technologies of the Catholic University of Louvain facilities host university and military molecular research activities into infectious diseases (human and animal).

Key Technologies and Core Competences:

¡¤                     Research and clinical applications: several innovative projects have been carried through within LTMA in the area of genomics. In the field of infectious diseases, AMT has developed expertise in molecular detection and the identification of bacterial and mycobacterial pathogens in human and animal samples, and on bacterial antibiotic resistance.

¡¤                     Service to industry: LTMA is part of many academic-industrial collaborations, in the context of research projects but also because of research contracts agreed with industrial partners.

AMT has the facilities and equipment necessary for molecular research on pathogens. These include a microarray platform (equipment for fluorescence or colorimetric detection; expertise for DNA or RNA labelling), sequence analyzer (conventional and pyrosequencer), real-time PCR, P2 and P3 facilities.

Role in the project

The LAMT will provide its expertise mainly for crisis management, as well as contributing in the field of detection and identification.

www.uclouvain.be

16 ¨C UNIVERSITÉ HENRI POINCARÉ of NANCY - UHP (FR)

Core business and skills

The Department of Environment and Public Health of the University of Nancy, headed by Professor HARTEMANN, is currently dealing with the evaluation of the impact of the environment on human health. 

Role in the project

It will take part in the cross evaluation of the existing health policies regarding bio-terrorism developed in European countries.

www.uhp-nancy.fr

17 ¨C UNIVERSITÄTSKLINIKUM BONN - UKB (DE)

Core business and skills

The Institute of Hygiene and Public Health of the UKB, directed by Professor EXNER, is one of the largest and leading institutions in the field of water hygiene, hospital hygiene and hygiene policy in Germany. It is also the office of the German society for hygiene and environmental medicine. In addition, the Institute has been selected as a WHO collaborating centre for health, promoting water management and risk communication.

Role in the project

UKB will participate in the review of the various health policies of the European countries. This aims at asserting the specific needs of the state members, in order to be able to suggest measures for developing a global response on a European scale.

www.uniklinik-bonn.de

18 ¨C UNIVERSITÉ PARIS 7 DENIS DIDEROT - UP7DD (FR)

Core business and skills

Through its department of microbiology, directed by Professor Andremont, the hospital Bichat is involved in the evaluation of antibiotic resistance (National References Centre). 

Role in the project

GHBCB will be involved in the development of tools for the education and training of first line professionals who would be involved in the response to an act of bioterrorism.

www.univ-paris7.fr

19 ¨C UNIVERSITY OF READING - UoR (UK)

Core business and skills

The Informatics Research Centre at the University of Reading is a new unit dedicated to bringing together research in the social sciences and humanities and research in information sciences. Dr. Adams teaches Social Legal and Ethical aspects of Computer Science. He has close connections with colleagues in the University of Reading School of Law, in particular those working in the areas of Human Rights and EU law. His other current work on the social and legal ramifications of developments in technology include work on the legal and economic problems with peer to peer file sharing and copyright issues, technological and psychological issues relating to illegal image distribution online, UK government policy on open source licensing of the results of government-funded R&D leading to the development of software. It is expected that expert assistance in privacy and human rights law on the international, EU and UK levels will be sought from appropriate colleagues with Dr. Adams bringing both his own legal studies and his understanding of the technical capabilities and limitations of potential systems to focus the attention of the project team on appropriate areas of study.

Role in the project

UoR will study the legal, social and ethical aspects which are linked to the developments in technology or medicine, and to the problem of balancing individual freedoms versus common goods. Moreover, it will have a role in the dissemination of the results, and thus be responsible for the development of the web portal

www.reading.ac.uk

20 ¨C MILITARY INSTITUTE OF HYGIENE AND EPIDEMIOLOGY- WIHE.PL

Core business and skills

The Military Institute of Hygiene & Epidemiology Warsaw, Poland (WIHE.PL) carries out research, developmental, diagnostic, prophylactic, and training activities as well as providing expertise and services in the fields of hygiene, epidemiology, microbiology, pharmacology, toxicology, radiobiology and defence against biological, chemical, and radiological/nuclear weapons. WIHE.PL participates in the development of systems for detection, identification, and countering of biological, chemical, and radiological contaminations of the environment; prevention against and management of health injuries caused by natural and industrial disasters and catastrophes; examinations of bio-medical effects of and development of protective measures against highly dangerous biological pathogens and toxins.

The main tasks of the Interdepartmental Section for Protection against Bio-terrorism include:

¡¤                     analysis of the current and future threats posed by biological weapons and bio-terrorism;

¡¤                     studies on emerging countermeasure methods against biological weapons and bio-terrorism.

 Role in the project

Through two entities, the Interdepartmental Section for Protection against Bioterrorism, (Warsaw, Poland) and the Biological Threats Identification and Countering Centre (Pulawy, Poland), the WIHE.PL will provide its expertise in the fields of detection and identification, of protection and decontamination, and of medical countermeasures. It will also contribute to education and training, and to the cross evaluation of the European member states health policies.

www.wihe.waw.pl

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Last Updated. Tuesday, 21-Nov-2007 14:22:09 GMT